Step 2: Click the relevant domain.
Step 3: Click Email settings.
Step 4: Select the mailbox which you would like to set up an auto reply for and click the Mailbox control panel button.
Quick tip: If you have enabled direct access you can skip steps 1-4 and access your mail settings at mcp.<yourdomainname.com> or mcp.livemail.co.uk.
Step 5: Click the Administration tab, then the Autoreply message button.
Step 6: Next to Mailbox autoreply status, click the Active radio button.

Step 7: Use the Autoreply message text text-box to enter the message that will be sent to anyone that sends email to this mailbox.
Step 8: Click the Save Changes button to activate the autoreply.
Step 2: Click Options in the bottom-left of the browser window.
Note: If you're using a browser other than Internet Explorer, the Options button will be at the bottom of the left-hand menu, towards the top of the screen.
Step 3: In the Out of Office Assistant section, click the I'm currently out of the office radio button.
Step 4: Use the text-box to enter the message that will be sent to anyone that sends email to this mailbox.

Step 5: Click Save and Close above the Out of Office Assistant section and the autoreply will be live.

You can also active the Out of Office Assistant from Microsoft Outlook 2003. See Outlook's interactive help for details.